Humans couldn't access this wisdom because angels and a flaming sword were assigned to prevent humans from coming near it.
But God has now revealed this wisdom in order to free mankind from the bondage of the sin of the tree of the knowledge of good and evil.
God has revealed them to us through His Spirit. For the Spirit searches all things, yes, the deep things of God. (1 Corinthians 2:10) "NKJV"
The hidden wisdom of God that is now revealed is Jesus Christ: the tree of life.
Christ the power of God and the wisdom of God. (1 Corinthians 1:24) "NKJV"
Understanding this wisdom is the sanctification and the resurrection. The redemption and the salvation of the world are revealed by the wisdom of God in our hearts. Since Christ is the wisdom of God, Christ in us is the redemption of God's people and the salvation of the world.
Christ Jesus, who became for us wisdom from God—and righteousness and sanctification and redemption (1 Corinthians 1:30) "NKJV"
Although this wisdom is the most valuable of everything on earth, God kept it secret and reserved it for specific individuals.
The things which God has prepared for those who love Him.” (1 Corinthians 2:9) "NKJV"
The wisdom of God is the wisdom of the cosmos meant for people that have come out of the chaotic old world to the harmonious new world. It is a wisdom stored up in the new world of the tree of life, such that they that belonged to the old world of the tree of the knowledge of good and evil were unable to access it.
Small wonder the apostle Paul said,
I do proclaim a message of wisdom to those who are spiritually mature. But it is not the wisdom that belongs to this world or to the powers that rule this world (1 Corinthians 2:6) "GNT"